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Mechanical trauma and local irritation represent the most common cause of injection site reactions

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In contrast, we deem it unlikely that the PCE of retatrutide is mediated via GLP-1R or via GIPR

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Possible side effects include: Nausea Headache Flushing Temporary increases in blood pressure If side effects are persistent, severe, or concerning, contact your provider

Clinical review 129: Oral cholecystographic agents and the thyroid