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The COVID-19 pandemic has fast-tracked their development as vaccine platforms for emerging viruses

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These molecules cannot directly stimulate T-cells, but they are involved in amplifying the signal derived from the interaction with an antigen via their interaction with other cell surface molecules, thereby leading to T-cell activation ( DPP-4 and Glucose Homeostasis The link between DPP-4 and glucose homeostasis was only identified after the intestinal hormone, glucagon-like peptide-1 (GLP-1) was found to be a DPP-4 substrate

Acceptable interventions include supervised diet programs, FDA-approved weight-loss medications (orlistat, phentermine-topiramate, naltrexone-bupropion), or bariatric counseling programs