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Crescentini, G
Sodium glycocholate liposome encapsulated semaglutide increases oral bioavailability by promoting intestinal absorption
Sci Rep 15 , 34673 (2025)
Consider the therapeutic target
In PCOS specifically, where excess adiposity and hepatic steatosis are common amplifiers of an already-present insulin-resistant state, this route alone would be expected to lower hyperinsulinemia and, by extension, reduce the insulin drive to ovarian androgen synthesis
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