repeated high doses may increase risk
VacA insertion facilitates mitochondrial depolarization, swelling, and the release of pro-apoptotic factors such as apoptosis-inducing factor (AIF) and cytochrome c ( Listeria monocytogenes , an intracellular pathogen, secretes listeriolysin O (LLO), a cholesterol-dependent cytolysin that destabilizes host membranes, including mitochondrial membranes (Li et al., 2021)
Cysteamine-colon and cysteamine-duodenum lesions in rats
How much intact peptide reaches systemic circulation by the oral route is genuinely uncertain, and any honest discussion has to say so
Emphatically, yes
If you want to try it, start with 2-5% concentration and use it only once weekly initially, building tolerance gradually