Yes, in people with B12 deficiency, injections can quickly improve energy and reduce fatigue
This was a recommendation both in the James Lind Alliance Priority Setting Partnership which PAS initiated and funded and in the NICE Guideline on B12 Deficiency which PAS initiated
Inform doctor about all ongoing medications
Some patients might move from, say, weekly injections to monthly injections as maintenance, then eventually to none if possible
Medical Oversight As with all peptides, it's recommended to work with a healthcare provider, peptide specialist, or longevity clinic especially if you have insulin resistance, metabolic syndrome, or are on medications
Do not go below 0.3g/lb even during aggressive caloric restriction