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79% do so when prescribed for obesity 27% of respondent plans that cover for diabetes have utilization management programs in place

Dietary adjustments are often the first line of self-management: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or heavily spiced foods, which can exacerbate loose stools Reduce intake of foods known to cause wind, such as beans, cruciferous vegetables, and carbonated drinks If constipation is the predominant symptom, increase soluble fibre gradually sudden large increases in fibre can worsen bloating and discomfort Stay well hydrated, particularly if experiencing diarrhoea, to prevent dehydration Timing and lifestyle considerations can also make a meaningful difference

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sCT when bound to AMYRs induce a CT-like receptor conformation 15 , while P32Y substitutions of CT analogues are also detrimental to affinity and potency at AMYRs 18,19