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The response held upremission inside 4 weeks, and steady through the rechallenge, which is at least a sign we were aiming at the right target ( 5.3 Rationale and pharmacokinetics of vortioxetinebupropion combination Picking vortioxetine over a standard SSRI or SNRI was a considered choice

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This suggests that metformin-induced glucose reduction is dependent on SGLT1 expression (Zubiaga et al., 2023)

Metformin is also associated with a rare but serious side effect called lactic acidosis, which requires emergency treatment in the hospital

Psychopharmacology 235 , 399408 (2018)

Both need to be informed, but coordinating that communication is your responsibility