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The serum B12 test alone misses many deficient patients, as high levels of methylmalonic acid and homocysteine have been identified as better indicators of B12 deficiency than the actual serum B12 level

The Science Behind B12 Absorption: Why Athletes Choose Injections Over Supplements The appeal of B12 injections over oral supplements comes down to one dramatic difference: absorption rates

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In cardiac models, Bock-Marquette et al., Nature 2004 reported that T4 activates integrin-linked kinase and Akt signalling, promoting cardiomyocyte survival, migration and improved function after coronary ligation in mice

Whilst B12 has a low risk of toxicity even at high doses, it is prudent to consider whether such high intake is necessary unless advised by a healthcare professional