Dietary strategies implicated in the prevention and treatment of metabolic syndrome
After the medication was discontinued, the study participants in both groups continued to receive lifestyle interventions for an additional seven weeks
This ensures maximum absorption and immediate benefits, bypassing the digestive system entirely
The primary goal was to assess the impact of tirzepatide compared to the placebo on the change in clamp disposition index, which combines measures of insulin secretion and sensitivity
According to the UK SmPC and European Public Assessment Report (EPAR), the most frequently reported side effects include nausea, diarrhoea, vomiting, constipation, abdominal pain, and decreased appetite
[1] [2] Effects attributable to glucagon receptor activation, such as increases in heart rate, were also observed and are subject to further evaluation in ongoing studies