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If diarrhea is severe, watery, or contains blood, it could be a sign of a serious infection called Clostridium difficile colitis

Exerts analgesic effect by down-regulating the TRPV1 channel in a rat model of arthritic pain

Nov 7 2025;doi:10.1056/NEJMoa2513032

Collagen in the skin became 44.6% less fragmented, skin hydration went up by 13.8%, elasticity improved by 22.7%, and wrinkles reduced by 19.6%

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DIM may also be taken as a supplement to achieve this same effect