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In terms of body mass reduction, semaglutide was more effective at 26 and 52 weeks

Do not use Trulicity if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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Hydration and Electrolytes With less food intake and occasional nausea or gastrointestinal side effects, dehydration can develop quickly when taking semaglutide

References: Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, et al