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However, the total drug exposure (measured as AUC) remains the same
They can detoxify cells and have both direct and indirect effects
That does not mean it is a good choice for continuously supplying that current
The self-assembled Bacteriphage MS2 VLP, which is modified with SP94 peptide and encapsulated with doxorubicin, cisplatin, and 5-fluoro-uracil to selectively transport and kill human hepatocellular carcinoma (HCC) in the Hep3B cell line, is a classic example of VLPs as targeted therapeutic carriers (147)
This is important because unchecked oxidative stress is associated with so many diseases including cancers, neurodegenerative diseases such as Parkinsons and Alzheimers, and heart disease that it can aptly be considered a killer
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