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The donor informed consent forms can be found in the Supplementary Materials)

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Critically, sophisticated EEG analysis confirmed no sedation in the classical pharmacological sense establishing that DSIP sustains natural sleep functions rather than inducing pharmacological sedation

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35 In addition, we measured 8-oxo-dG, a commonly used biomarker for assessing oxidative DNA damage during inflammatory and pro-oxidant exposures

Published preclinical studies have examined TB-500 in the context of wound repair models, cardiac tissue research, and inflammatory response modulation