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Optic nerve injection of lysophosphatidylcholine (LPC) induced localized myelin loss in MS mice, significantly elevating Fe 2+ and MDA levels, while reducing GSH, NRF2, and GPX4 expression, as well as iron reactive element binding protein 2 (IREB2) in optic nerve tissue

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The breadth of effective administration routes is unusual for a peptide and is part of why BPC-157 attracts ongoing interest in connective tissue