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70 Additionally, lactylation at K91 of transcription factor EB (TFEB) impedes it from interacting with E3 ubiquitin ligase WW domain-containing E3 ubiquitin protein ligase 2 (WWP2), thereby inhibiting TFEB ubiquitination and proteasome degradation and eventually augmenting TFEB activity
People with less body fat are more at risk
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This is local discomfort, not a sign the treatment has gone wrong
Alcohol may affect blood glucose regulation and can worsen gastrointestinal symptoms
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