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Patel, Anuradha P
The hydroxyl radical is generated by both aconitase inactivation and MPO activity, and promotes the formation of 8-oxo-dG
It plays a significant role in tissue remodeling, immune regulation, and cellular repair
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Purified recombinant 3MST and lysates of COS cells expressing 3MST showed that Cys-SSH and GSSH were produced in the presence of physiological concentrations of cysteine and glutathione, while those with longer sulfur chains, Cys-SS n H and GSS n H, were produced in the presence of lower than physiological concentrations of cysteine and glutathione
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