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Antioxid Redox Signal 2002
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True gynecomastia involves firm glandular tissue under the nipples, often triggered by hormonal shifts, medications, or medical conditions
N-acetylcysteine, an efficient thiol antioxidant and GSH precursor, was able to inhibit ATG by impeding the lipidation process of LC3 mediated by ATG4, the activity of which is modulated by hydrogen peroxide (Scherz-Shouval et al., 2007)
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These properties align perfectly with the pathophysiology underlying GERD
