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This difference was likely attributable to the insufficient inhibition of excessive GJ proteins in hepsin / mice in response to the lower 2APB dose of 1 mg/kg, lending further support to the hypothesis that hepsin may help reduce APAP toxicity by regulating the expression of hepatic GJ proteins

Group 4 got LPS (250 L/kg body weight) from day 1 to day 7 and MSG from day 8 to day 14

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