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Many users see excellent results with evening-only use, which simplifies morning routines

Consider increased clinical or laboratory monitoring when used concomitantly with other oral medications that have a narrow therapeutic index or that require clinical monitoring

Clinical use requires individualized medical evaluation and supervision

South Korea is becoming a closely watched market because MFDS has moved to classify liraglutide, semaglutide and tirzepatide-containing obesity drugs as medicines with misuse risk when used outside treatment purposes

Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has garnered significant attention for its effectiveness in managing type 2 diabetes and promoting weight loss

This Review dissects the mechanistic intricacies of NRF2 signalling, its cross-talk with biological processes and its far-reaching implications for health and disease, highlighting key discoveries that have shaped innovative therapeutic approaches targeting NRF2