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I also wish Id appreciated how important hydration is

Persistent fatigue , tingling in the hands or feet, difficulty concentrating, or headaches could indicate B12 deficiency even with supplementation

People with more visceral fat (apple shaped) tend to have higher cholesterol, blood sugar, and blood pressure at a given bodyweight than those whose fat is more evenly distributed around the body (hourglass or pear shaped)

In these trials, the medication was started at a very low dose, and the dosage was escalated gradually to maximize efficacy while minimizing early adverse effects, particularly gastrointestinal events that were consistent with Phase 2

The Phase 2 trials showed that participants losing under 5% by week 12 were rare, accounting for only 8% of the cohort, and that most of them eventually caught up through the next titration phase