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Use healthy fats strategically
doi: 10.1016/j.cmet.2017.04.013 70 GronebergD.VoussenB.FriebeA
The cost savings could make these drugs accessible to patients who simply couldnt afford them before
Usage Instructions: Take exactly as prescribed by your healthcare provider Swallow tablets whole with a small amount of water at least 30 minutes before eating, drinking, or taking other oral medications The typical starting dose is 3mg and adjusted in coordination with tolerability of side effects and effectiveness Maintain a balanced diet and regular exercise program while taking this medication Warnings & Precautions: Do not use if you have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) Use with caution if you have a history of pancreatitis, diabetic retinopathy, or kidney disease Possible side effects include nausea, vomiting, diarrhea, abdominal pain, or decreased appetite
Psychiatry (2019)
Obtain comprehensive baseline labs: TSH, free T4, free T3 Thyroid antibodies (TPO and thyroglobulin if not previously checked) Complete metabolic panel HbA1c and fasting glucose Lipid panel Vitamin D and B12 (commonly deficient in hypothyroidism) During Treatment When to Contact Your Provider Reach out if you experience: Unusual or worsening fatigue not explained by semaglutide initiation New or returning brain fog or cognitive difficulty Constipation that does not improve with typical measures Heart rate changes (especially sustained bradycardia) Cold intolerance or dry skin changes Weight loss plateau despite medication adherence Hair loss beyond what is expected with weight loss Mood changes including depression or anxiety Semaglutide Alternatives for Hypothyroid Patients For patients who cannot take semaglutide or prefer alternatives, several options exist: Tirzepatide (Mounjaro/Zepbound): Dual GLP-1/GIP agonist with potentially greater weight loss
