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Towards personalized allele-specific antisense oligonucleotide therapies for toxic gain-of-function neurodegenerative diseases
If left untreated, it can lead to complications like blindness, kidney failure, heart attacks, stroke and lower limb amputation
Reported Adverse Effects Reported adverse effects from online forums cited in a 2025 systematic review (PMC12313605) included: Anxiety and panic attacks Depression and anhedonia Insomnia Heart palpitations Fatigue and weakness Loss of appetite These anecdotal reports cannot be verified as directly caused by BPC-157 versus contamination, incorrect dosing, or concurrent conditions, but they raise concerns that the peptide might paradoxically worsen mental health in some individuals
Differential effects of glutathione S-transferase pi (GSTP1) haplotypes on cell proliferation and apoptosis
