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Similarly, fisetin, a flavonoid found in strawberries and other fruits, activates SIRT1 by increasing NAD + levels while also reducing oxidative stress and inflammation 179 (Fig
Most evidence to date reflects changes in downstream or adaptive pathways, such as inflammation, mitochondrial function, and metabolic regulation, rather than direct modification of the primary sources of molecular damage
On the contrary, noxious effects of statins in PD were also experimentally investigated
However, no significant difference was found in the subgroup analysis [183]
m: n = 3-4 biological replicates
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