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A study revealed that oxidative stress, hepatic lipid deposition, insulin resistance, and mitochondrial dysfunction are all present in high fat-induced obese mice (117)

Mechanistically, circadian control of CI probably reflects the intersection of substrate routing and time-of-day coordination of CI biogenesis, stability and activity

De Palo E, Gatti R, Sicolo N, Padovan D, Vettor R & Federspil G (1981): Plasma and urine free L-carnitine in human diabetes mellitus

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