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Jacobson TA, Maki KC, Orringer CE, Jones PH, Kris-Etherton P, Sikand G, et al

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Initial weight loss varies, but most patients notice appetite reduction within days and see 2-5 pounds on the scale within the first 4 weeks

In short, trial data describe early appetite and satiety shifts, followed by progressively larger body-weight changes as the dose climbed and treatment continued

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