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doi: 10.4103/cjp.cjp_13_21 69 YazganBAvcFMemiGTastekinE

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2.3 Neuroinflammation Some studies have shown that berberine activates macrophages and increases their phagocytic function, increases the production of interleukin (IL)-1, and enhances non-specific immunity, can be used as a neuroprotective agent to prevent Alzheimers disease (Kumazawa et al., 1984

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Conversely, blocking glutathione transport from the periplasm into the cytosol by deleting GsiC, the inner membrane component of the GsiA-D ABC Transporter (Suzuki et al., 2005

Epigenetic mechanisms are functionally essential for regulating gene expression 1,2