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Jump to: GLP-1s for type 2 diabetes | GLP-1s for weight loss | Side effects and safety | Take home message GLP-1 receptor agonists (GLP-1s) are a class of medications approved for individuals living with type 2 diabetes and obesity to help lower blood glucose levels (blood sugar) and support weight loss

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Hypoglycemia: While GLP-1 medications themselves rarely cause hypoglycemia (low blood sugar) when used as monotherapy, combining them with a mechanism of action that causes hypoglycemia such as insulin or sulfonylureas can increase the risk of hypoglycemia

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