This is common in the supplement world, as clinical trials involving pregnant participants are ethically complex and rare
Tirzepatide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes
After 40 weeks, 78% to 85% of adults taking Mounjaro achieved an HbA1c below 7%, compared with 23% of adults taking a placebo
If side effects become intolerable despite management strategies, your healthcare provider may consider dose adjustment, temporary treatment interruption, or alternative therapeutic options
FDA hasnt yet approved it for clinical use
In summary, these data provide evidence that long-term IGF-1R blockade with mAbs is feasible, well tolerated, and can recapitulate effects observed with genetic disruption of IGF-1R signaling on lifespan