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For instance, blood vessels provide a route for the arrival of immune cells to the tumor, and through the expression of adhesion molecules (selectins and integrins), and the secretion of chemokines and cytokines, BECs participate in immune cell activation, migration, and recruitment, and play a crucial role during the extravasation of immune cells (89)

Front Immunol (2019) 10:1033

Every patients experience is different

Acknowledgements This research was supported in part through a University of Michigan Developmental Research/ GI SPORE (P50 CA130810) Pilot Award

Complications, including obstruction and perforation, may occur