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Seventh, our primary efficacy analyses targeted an on-treatment estimand and, therefore, may overestimate effectiveness compared with a treatment-policy (all-exposed) approach

This reflects rapidly growing adoption as more adults use GLP-1based therapies to support clinically meaningful weight loss and health outcomes

10.1016/j.dsx.2020.11.004 13

Diabetes Ther (2021) 12:80111

Amy Marsteller breaks down the fascinating science behind GLP-1 medicaitons, how they work, who may qualify, and what patients should consider before starting treatment

GLP-1 medications have been studied extensively in large-scale clinical trials and are considered safe for most eligible patients when used as prescribed