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The anti-inflammatory and anti-oxidant mechanisms of the Keap 1/Nrf 2/ARE signaling pathway in chronic diseases

Primary human lung fibroblasts for in vitro experiments were isolated from histologically normal regions adjacent to resected lung tumours

F., Hasan, A

BPC-157/TB-500 10+10mg $160.00 Volume discounts Auto-applied at checkout Free shipping on orders of $200+ Compound Identity COMPOUND NAME BPC-157 and TB-500 peptide blend SYNONYMS Body Protection Compound-157 (BPC-157), Thymosin Beta-4 Fragment (TB-500) CAS NUMBER BPC-157: 137525-51-0 TB-500: 77591-33-4 MOLECULAR FORMULA BPC-157: C 62 H 98 N 16 O 22 TB-500: C 212 H 350 N 56 O 78 S MOLECULAR WEIGHT BPC-157: 1419.53552 g/mol TB-500: ~4963.49 g/mol STRUCTURE Synthetic tetrapeptide PEPTIDE SEQUENCE BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val TB-500: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Lys-Asp-Lys-Ser-Ile-Lys-Asn-Asp-Lys-Pro-Thr CHEMICAL STRUCTURE BPC-157: TB-500: CHEMICAL STRUCTURE BPC-157: C 62 H 98 N 16 O 22 TB-500: C 212 H 350 N 56 O 78 S Mechanism of Action BPC-157 is believed to act via modulation of nitric oxide pathways, angiogenesis induction, and cytoprotective effects through VEGFR-2 and FAK-paxillin pathways

Pellagra: dermatitis, dementia, and diarrhea

Lee MC, Lin YF, Hu S, Huang YL, Chang SL, Cheng CY, et al