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Effects of insulin deficiency or excess on hepatic gluconeogenesis flux during glycogenolytic inhibition in the conscious dog

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While the specific mechanism causing the effects on the gastrointestinal tract are not fully elucidated, studies suggest GLP-1 and its analogues likely exert effects on the vagus nerve and inhibit cholinergic neurotransmission in the gastrointestinal system to prevent movement of the intestine

Antibodies were obtained from Abcam (CYP8B1, ab191910

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Semaglutide is an injectable medication that supports healthy weight loss by helping regulate appetite and blood sugar levels