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However, whether or not albuminuria is a clinically relevant renal outcome remains unclear

They are the standard of care for this type of intervention

Agonists are under intense study, as different kinds of hormone agonists may be useful for a variety of medical processes, including the treatment of prostate cancer, endometriosis, and more

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Based on available Phase 2 data, both agents share a side-effect profile broadly consistent with other medicines acting on metabolic hormone pathways, though the triple-agonist mechanism of retatrutide introduces some additional considerations