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A 2019 randomized controlled trial of lipotropic injections (methionine, inositol, choline, B12) versus saline placebo in 120 participants on ad libitum diets found 0.8 kg (1.76 pounds) difference at 12 weeks, not statistically significant (p=0.18) (Karbalay-Doust et al., Journal of Research in Medical Sciences , 2019)

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The treatment works best when done regularly

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Start Understand the mechanism Use the quick facts, pathway overview, and research notes to understand why the compound is discussed

For a broader three-way look at how AOD-9604 stacks up against both MOTS-c and Tesamorelin together, see the AOD-9604 vs MOTS-c vs Tesamorelin comparison