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The main function of GPX4 is to catalyze the glutathione GSH-dependent reduction of membrane lipid peroxides to their corresponding alcohols, thereby protecting cell membranes from oxidative damage (62)

Teichert, J., Hermann, R., Ruus, P., and Preiss, R

10.1016/j.biomaterials.2019.04.034 57 LiuD.ShuG.JinF.QiJ.XuX.DuY.et al (2020a)

Saghazadeh A, Rezaei N

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When given orally, stomach acids and enzymes destroy glutathione before it is absorbed into the bloodstream