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A 2024 systematic review and meta-analysis suggested NAC may be helpful as an add-on therapy for adults with moderate-to-severe OCD, but results have not been consistent across all psychiatric conditions or studies.33 Researchers are still working to determine which patients are most likely to respond and whether NAC's benefits are large enough to produce meaningful improvements in day-to-day functioning

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On the other hand, creams or lotions are less invasive but might require consistent application over an extended period with potentially slower results

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For these patients, carnitine levels should be monitored, and supplementation discussed with their nephrologist

Common: nausea, fullness/early satiety, heartburn, constipation or loose stool, decreased appetite