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Notably, unlike older diabetes medications, GLP-1 agonists carry minimal risk of hypoglycemia because their insulin stimulation is glucose-dependent ( [2] )

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However, if you take oral semaglutide (Rybelsus), timing is importantit must be taken on an empty stomach with no more than 4 oz of plain water, at least 30 minutes before eating any food, including bananas

Some cases have been severe enough to require hospital treatment

While they were originally developed to treat type 2 diabetes, they have now been linked to multiple other benefits, cardiovascular and otherwise

When prescribed for weight loss in patients without diabetes, this constitutes off-label usea practice permitted under medical judgment but outside the FDA-approved indication