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consistently for at least one month for the best results

Research Summary The preclinical foundation for retatrutide was established by Coskun et al

It works as a glucagon-like peptide 1 (GLP 1) receptor agonist, which means it boosts insulin secretion in response to glucose and reduces the amount of ghrelin produced by the stomach

Alternatives include other GLP-1 receptor agonists (such as dulaglutide or liraglutide), SGLT2 inhibitors (such as dapagliflozin or empagliflozin), DPP-4 inhibitors, or insulin therapy

Test glucose response carefully in the early weeks if you use any of those

10.1038/nrc883 40 CuiT.DaiX.GuoH.WangD.HuangB.PuW.et al (2024)