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This form further donates its methyl group to a B12 molecule, forming methylcobalamin

The strongest association signals for baseline GR/HGA were within a locus on chromosome 7 containing two central genes: TAC1 (protachykinin-1) that has been linked to depression and anxiety 85 and ASNS (asparagine synthetase [glutamine-hydrolyzing]) that is an important enzyme, the deficiency of which leads to substantial neurodevelopmental deficits 86

LW: Writingoriginal draft, Resources, Data curation, Conceptualization

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doi: 10.1016/j.cell.2017.11.048 163 ChenXKangRKroemerGTangD