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Others dismiss it entirely because large-scale human clinical trials are still lacking

No pattern of delayed side effects has emerged in community use spanning years

[14] Doctors usually recommend intramuscular injections, which is what we're describing

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Both were removed from FDA 503A Category 2 on April 22, 2026, but neither is on Category 1 either

The International Society of Sports Nutrition (ISSN) concluded that creatine is the most effective nutritional supplement available for athletes interested in increasing high-intensity exercise capacity and lean body mass [12]