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Microdosing in this context means taking smaller-than-prescribed doses of semaglutide, often far below the clinically tested amounts

There is no strong clinical evidence showing it can safely or effectively treat opioid withdrawal

Current clinical guidance and prescribing information do not require a washout period when switching between any GLP-1 receptor agonists, including switches between pure GLP-1 drugs and dual GIP/GLP-1 agonists

Breastfeeding parents need an average of at least 500 additional calories daily, and GLP-1s can significantly decrease appetite and compromise energy and nutrition

Pregnancy and lactation represent relative contraindications given absence of human safety data in these populations despite reassuring preclinical reproductive toxicology studies

During Emergency Care: Emergency department physicians and urgent care providers need complete medication lists to make informed decisions