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One newer option being studied is cagrilintide, an investigational injectable developed by Novo Nordisk, the same company behind Ozempic and Wegovy

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Its a peptide derived from a protective protein found in the stomach

In a randomized trial, Gelesis100 produced modest placebo-adjusted weight loss

SURMOUNT-2: tirzepatide with type 2 diabetes The second trial focused on adults who had both obesity and type 2 diabetes, a population that traditionally loses less weight with GLP-1 medications because insulin resistance and metabolic dysfunction create additional barriers