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We recruited 28 patients with stable schizophrenia and 45 healthy participants matched for age, gender, and parental socio-economic status

For example, NMR-titration experiments of non-glutathionylated poplar GrxC4 or ScGrx8 with GSH required high glutathione concentrations to detect chemical shifts 47,48 (and titrations of active site serine mutants with GSSG cannot discriminate between both glutathionyl moieties)

References Healthline

& Micluia, I

Oxidation of fatty acids and tricarboxylic acid cycle intermediates by isolated rat liver mitochondria

ROS are the main molecules involved in the role and mechanism of GPxs in the development of diseases ROS, reactive oxygen-containing molecules, are the normal products of aerobic reactions in humans, such as oxidative respiration in mitochondria [24]