Vitamin B12 injections assist in weight loss by helping with digestion, supporting cellular respiration to speed up metabolism, increasing energy levels to encourage activity, maintaining an effective metabolism for breaking down carbohydrates and fats, and potentially suppressing appetite
If the shot is given directly into a vein, a lot of the Vitamin B12 might end up being lost when someone pees
Preclinical studies in mice demonstrate significant reductions in fat mass and body weight without changes in food intake
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The methodological quality of the included studies, as assessed through the Jadad and NewcastleOttawa scales, varied from moderate to high, while the GRADE assessment indicated moderate certainty of evidence for serum vitamin B12 increase and low certainty for homocysteine reduction
PMID 19153403