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Interestingly, ammonia detoxification by CD8 + T cells promotes their stemness, which is associated with antitumor immunity in a mouse melanoma model

Symptom Monitoring: Even though serious adverse events did not occur in trials, individual monitoring for headache, gastrointestinal symptoms, or unusual effects allows for early detection of tolerability issues and appropriate management adjustments

6.3.2 Reproductive health monitoring 6.3.1.2 Biomarker-based surveillance Annual biomarker screening for EED exposure, including urinary BPA, serum PCBs, and seminal oxidative stress markers, enables early identification of reproductive risks before clinical manifestation (138)

Should be medically supervised when given intravenously

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3j and Supplementary Fig