Similar GH-releasing potency
Excessive ROS damage to vascular endothelial cells disrupts the balance between vasoconstrictive and vasodilatory factors, impairing the hemostatic contractility of spiral arteries
Bacterial mucosal immunotherapy with MV130 prevents recurrent wheezing in children: A randomized, double-blind, placebo-controlled clinical trial
Characteristics of PFIC and PFIC-related diseases in paediatric populations PFIC causes progressive intrahepatic cholestasis in newborns, infants, and children
In vitro experiments confirmed that A 25-35 treatment significantly inhibited the activation of the NRF2/SLC7A11/GPX4 signaling pathway in HT22 cells, upregulated the expression of Fe 2+ , TFR1, ACSL4, MDA, and GSSG, and decreased the expression of FTH1, SOD, and GSH, as well as the GSH/GSSG ratio, resulting in dysregulated neuronal iron metabolism, impaired amino acid antioxidant systems, mitochondrial dysfunction, and ferroptosis, which ultimately promoted neuronal injury
(6) Hu R, Wang Z, Peng Q, Zou H, Wang H, Yu X, Jing X, Wang Y, Cao B, Bao S, Zhang W, Zhao S, Ji H, Kong X, Niu Q