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elegans and ameliorated mutiple aging-related phenotypes, including enhanced resistance to oxidative and thermal stress, improved motility, pharyngeal pumping, defecation rhythm, and reduced lipofuscin/lipid accumulation

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Carbamidomethylation of cysteines was defined as fixed modification, while acetylation of protein N-terminal, oxidation of Methionine was set as variable modifications for database searching

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The GPX family contains eight members (GPX1-GPX8), of which GPX1-GPX4 and GPX6 (human) members have an active center of selenocysteine, which is an important selenoprotein in mammals (Table 1)

In this study, we found that it was not the higher concentration of GSH that promoted tumour cells more significantly, but higher concentrations of GSH had an inhibitory effect on tumour cells instead (Supplementary Fig