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Several mid-stage trials will read out in 2025 to provide important proof points for novel MoAs and their potential for differentiation, e.g., Lillys bimagrumab (activin/myostatin type II receptor inhibitor) in combination with semaglutide, aiming to deliver weight loss while preserving muscle mass (phase 2b)

Ipamorelin binds to ghrelin receptors on the pituitary gland, switching them on in the same way that ghrelin naturally would

It also has to manage appetite, metabolic flexibility, and inflammation in a way that allows progress to continue long enough to become visible

W h e n confronted with the magnitude of the educa- tional problems of the future, the temptation will yet again beMichel Souchon 392 to place excessive hopes on the old or new media

Not suitable for children under 15 years of age or pregnant women: Should only be used under medical or dietetic supervision