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Lactobacillus reuteri DSM 17938 has evidence for improving GI motility

Appetite suppression is significant

The combination of reduced food volume and slower gastric transit creates conditions favoring this issue

Xolair (Roche): $3.7B US sales in 2025, losing exclusivity now after 23 years Only Celltrion has an approved biosimilar ready Pomalyst (BMS): $2.34B US sales at risk One of many drugs losing patent protection from BMS recently/upcoming Opsumit (J&J): $1.63B US sales Already facing direct competition from Merck's Winrevair 10 generic manufacturers are ready to go with FDA approval Januvia/Janumet (Merck): $1.27B US sales 25+ generic settlements already in place Also losing US exclusivity: Simponi (J&J): $1.19B - autoimmune TNF blocker Mavenclad (Merck KGaA): $716M - relapsing MS Gattex (Takeda): $707M - short bowel syndrome Trintellix (Takeda): $698M - major depressive disorder Briviact (UCB): $652M - epilepsy Xeljanz (Pfizer): $625M - rheumatoid arthritis --- Patent expiry doesn't necessarily mean competition

El Phytosonic, tecnologa con efecto ultrasonidos y succionador, dando como resultado un efecto quemagrasas y antiinflamatorio

These contractile effects of retatrutide are mediated by GLP-1R