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The peptides influence on over 4,000 human genes means its effects extend well beyond the dermis

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Life Sci 284:119911 Sayed AM, Abdel-Fattah MM, Arab HH, Mohamed WR, Hassanein EH (2022) Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: role of TLR4/NF-B and c-Fos/c-Jun pro-inflammatory pathways and PPAR-/SIRT1 cytoprotective signals

These different amino acid sequences, these different peptides, that is, are designed to stimulate different

Yes, under the wrong conditions